The New Debrecen Journal of Medicine

September 17, 2004; Issue 14

FMSA

Vioxx Increases MI Risk

According to a new large study by the Food and Drug Administration (FDA), patients taking Vioxx (rofecoxib) had a 50% greater chance of myocardial infarction (MI) and sudden cardiac death compared to individuals using Celebrex (celecoxib). The study also found that patients taking the highest recommended daily dosage of Vioxx had 3 times the risk of heart attack and sudden cardiac death as those not taking standard NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).

Researchers discovered the potentially damaging effects of Vioxx after analyzing the medical records of 1.4 million people!

Both Vioxx (rofecoxib) and Celebrex (celecoxib) are anti-inflammatory drugs and are members of a family called COX2 inhibitors. These selective COX2 inhibitors were designed to reduce the risk of gastro-intestinal damage caused by non-selective COX inhibitors (like Aspirin and other NSAIDs).

Vioxx is a $2.5-billion-a-year best-seller drug. Most patients take daily Vioxx doses of 12.5mg or 25mg for arthritis, but a higher dose of 50mg has been approved for treatment of pain.

Based upon the evidence in this study, the FDA recommends that doctors should not prescribe high-dosage Vioxx, and patients shouldn't take it.

Vitamin E Does Not Prevent Disease

Findings from a new study suggest that, in contrary to previous thoughts, vitamin E is not useful in the prevention or treatment of cardio-vascular disease. The researchers warn that the use of vitamin E (also known as tocopherol) and other over-the-counter agents with

unproven results can lead to the underuse of agents which have proven efficacy.

The findings are based on an analysis of data from several randomized trials that looked at vitamin E's ability to treat or prevent cardiovascular disease. In the trials it was proven that the usage of vitamin E has no significant effect on morbidity and mortality of any important cardiovascular diseases. In particular, there was no decrease in the risk of myocardial infarction, stroke, or overall cardiovascular death. The results provide strong support that vitamin E supplementation has no statistically significant or clinically important effects on cardiovascular disease. However, the researchers did not advise to refrain from using vitamin E.

Vioxx - Structure

Editorial

Dear students!

Here we are again walking between the lecture-halls of our medical university. The summer vacation ended, a new academic year has just started, and we each have many plans, hopes and dreams for this new year. For some of us, this is the first year in Debrecen. For others, this is our 2nd, 3rd, 4th, 5th or even 6th year in Debrecen. We, the "seniors", would like to welcome all the new students and wish them success in their studies. Also, we wish them a fast and easy adaptation into this foreign and unfamiliar country.

Many of the "veteran" students already know this newspaper that you are holding in your hands now. This journal is prepared by students, and is intended for students. The aim is to bring to your attention many new and interesting medical/scientific news from around the world. However, the newspaper has much room for social content. We encourage and

look forward to receiving articles from students about any topic. E-mail us interesting stories, recommended websites and so on. Our address is: tndjom@yahoo.com (`tndjom' is: The New Debrecen Journal Of Medicine. Duh).

Medicine is a developing and ever-changing field, and so, if you desire to be good, it is important to keep up-to-date. New discoveries regarding the pathophysiology of many diseases, new diagnostic examinations and new medications are revealed almost every day. The editors of this newspaper search for these new publications and bring them to you. The articles that appear in this newspaper are collected from well-known international medical journals (like the New England Journal of Medicine, The Lancet, The Journal of the American Medical Association, the British Medical Journal and others). Obviously, the Internet is also used to collect the most up-to-date material.

In order to make these collected articles more "student-friendly", we shorten and edit them. We hope that this journal will help you increase your knowledge, and maybe, who knows, it may even help you in an exam.

This newspaper is rather new. It was first published on February 2003 by four enthusiastic students who saw the great potential that such a newspaper has. Later on the newspaper became the venture of a single student who took it upon himself to keep this creation alive. And so it was until recently when new people joined the team. But maintaining this creation alive and running requires a lot of work and "fresh" people are always needed. So, if you have a craving for writing, or if you simply like the printed media, please E-mail us.

Good luck to everybody and SHANA TOVA U'METOOKA (Happy New Year) to the Israelis.

Ophir Bar-On

Chief Editor



Page 2

September 17, 2004; Issue 14

The New Debrecen Journal of Medicine


Message To The New Breed

A lot of new students are coming this year, not only in Medicine, but also in Dentistry, and the "neonate" faculty of Pharmacy. We wish them all good luck but would also like to point out a couple of mistakes that keep happening the last five or six years.

Welcome Home: Scary, or sad as it sounds, this is your new home. With God's help you will stay here

that is not necessarily bad. Somebody else's culture is not of threat to you, if you are a master of yours. If your own culture lives in you, and it's not an imposed set of behavioral rules, then drinking some Chinese tea is of no harm to anyone.

Make good friends with your classmates: Do not isolate yourselves, even though I know that the idea, of watching DVD's alone for the rest of your studies is tempting, the people you are going to meet in your first couple of years here, are the one that are going to stay. Help them and help each other. It is not fun, to wake up one day after five years in Debrecen and realize you have none to go for coffee with.

Help Your Classmates: It's a mistake to think you are Gladiators in an arena. You don't try to kill each other in order to survive. You are in one group. Imagine yourselves as row men in a boat, if everyone rows his way you will only get there slower. Share what you have, you will not loose anything, and most probably you will get something good in exchange. Anyway do you really think that because of these papers, you will get a five, and your classmate is going to fail?

Don't Group-Out: People from the one or the other year, country, and religion or whatever. The previous are important stuff, for me and for everyone, but you need to talk about the same thing, with the same people all the time. Sometimes student parties look like a bunch of separate companies that sit together in the same pub. There is no intercommunication between them. Even if they were alone in some private house, they still wouldn't mind it.

Finally…learn this f* language: Hungarian is hard, doesn't look like any other European tongue. So what? You have no idea how easier your life will be once you start speaking it. Go to classes in the first years, make friends with Hungarian students, and talk to the old lady in the non-stop. If you are a little social it will come by itself. Locals do not understand Hungarian unless if they are spoken to correctly, don't give up and make sure to pick up as much as you can. It takes time and it's hard but you will not regret it… trust me in this one.

Try to manage my few advises and you won't loose. You are the "generation of the desert" since older years are almost finishing and they have no will, or energy to change anything in their behaviour...

for years. Make your presence permanent. You will be miserable waiting for your life to start every time after the exam period ends. Hungary is a beautiful place to be (especially the other region of it! The one that starts from Danube and on…) don't forget, you might be able to keep your friends back home, but you will definitively loose your social circle. It will make you bitter and miserable to think "…oh well I will only stay here five years more…" if you think I'm lying look at the higher years for a proof.

Don't listen to anyone: your classmates, older students, etc. will try to scare you off! Put two corks in your ears and go on. They will fill you up with fears, ideas and ideals. None of these people is for real; you do not need anything else but yourself, correct orientation, your friends and discipline. None wants to fail you and the colour of your socks this or the other day has nothing to do with it.

Keep on having these corks on: You will hear rumors about EVERYONE. He did this, she did that, notes, papers are going around like the Flying Dutchman. Everyone knows about him but no one saw him ever. If you hear these guys, you will spend your next five/six years in a psycho thriller. Do not hear rumors, do not believe rumors, do not reproduce rumors and finally do not create rumors. You will not understand how real my words are until you hear other people talking about you.

Have your eyes open: Even though you close the ears… you are in a place where cultures meet, people meet, habits meet. A lot of beautiful people with a lot interesting stuff to learn from them. Countries you never heard about, religions you just knew vaguely about, food you never tasted before. If you are a smart person, you will try to come into contact, to exchange habits. In the end

of the day you will not recognize yourselves and



Page 3

September 17, 2004; Issue 14

The New Debrecen Journal of Medicine


Tips From The Elders

Some advice to the new students... First of all, obviously: study. This is what you came here to do. Don't cut corners and don't give up. If becoming a medical doctor is your dream, be prepared to invest in order to reach that target. The road will be long and difficult, but the end point is out there. The daily life is not easy: lectures, seminars, labs, self-controls... these can all be a nightmare. And although the clock on each day will seem to move slowly, you will be surprised to notice when suddenly a week will end, and then, all of a sudden it will be week 4, and then week 10 and then the semester will be over! Believe me, time will fly quickly. More than you can imagine.

Try to enjoy your stay in Hungary. Learn the language. Get to know the Hungarian people (your fellow students and your neighbors in the building). Go out in Debrecen. Walk around the city center whenever you can. Look around. Debrecen has more to offer than you imagine. Go to the museum. Go to the theater (they have fine operas and concerts there). Check out the botanical gardens and go to the zoo. Climb up the tower of the yellow church and see the view. Explore. Spend time with students from different countries. Learn from them. This will expand you mind and your horizon. Go to the street fairs. Taste bizarre local foods (not only McDonalds). Buy food in the farmers' market (not only in the Interspar). Walk through the park, not around the park. Travel inside Hungary as much as you can. Take a train to

Budapest; rent a car and drive to Eger; visit

Esztergom; hike in the Bukk mountains near Miskolc (they are only one hour away from Debrecen and you can even ski there during the winter).

Don't expect to "have" a lot of free time to do all these activities. Instead, you should "make" time for them. Believe me, you won't regret it. Looking back on life you will regret the things that you haven't

done, and not the things that you did. That is, nothing bad will happen to your achievements in school if you take a weekend vacation every-now-and-then. You can always make up for some lost hours of studying.

And one more important piece of advice: remember that you are studying for yourself. At the end of this long road you will stand in front of a patient and you will need to help him or her. It will be very unfortunate if you won't recognize the illness just because you decided to "skip that chapter in physiology" or "pass-over that topic in biochemistry". Medicine is a complex subject, but it is also beautiful and fascinating, so try to enjoy what you study. You will benefit from this attitude.

Last word: recently there were some incidents of violence between local Hungarians and foreign

students. This is both serious and dangerous. Sadly, despite the fact that we are in the 21st century, and that most of the world has learned to avoid racism, we can still stumble across xenophobia here. We are foreigners in this country, and some locals don't appreciate our presence. In an attempt to raise the awareness to this subject, the FMSA transferred an official complaint letter to the heads of the university, to the mayor and to the police. However, until these will carry out their influence, we recommend that foreign students do their best to avoid any commotion or fight. Be humble. Be quiet. Don't be right, be smart.

Take care of yourself and good luck!

Digital copying & laser printing!

All office services available!

Now open in the new student dorms (hostel 4)!

Open every day from 12:00 till 22:00

Question? Call: 06(20)4684226 or 06(30)4684226



Page 4

September 17, 2004; Issue 14

The New Debrecen Journal of Medicine


AIDS Where Do We Stand?

In microbiology and pathology lectures you will learn about the virus that causes the Acquired Immune Deficiency Syndrome (AIDS). You will learn about the proteins that the virus is made of and how exactly it attacks the CD4 cells. But this is just one side of the picture, the "academic side". This article tries to show the other side. Don't forget that behind the academic facts of HIV there are people suffering and dying.

As the AIDS pandemic enters its 24th year,

The specific nature of the epidemic, however, continues to vary both among regions and within countries.

Globally, "unprotected sexual intercourse between men and women is the predominant mode of transmission of the virus," according to the World Health Report 2004, released by the World Health Organization (WHO).

The updated statistics highlight the global disparities in deaths due to AIDS. Without treatment, it typically takes 10 years for HIV infection to progress to full-blown AIDS. A total of 2.2 million people died of AIDS in sub-Saharan Africa in 2003 (accounting for 76% of the global total). By comparison, in Western Europe, where effective treatment is widely available, only 6000 people died of AIDS in 2003.

AIDS in children remains concentrated in sub-Saharan Africa. More than 2 million women with HIV infection give birth each year. Despite the availability of effective antiretroviral treatment, about 630,000 infants contract HIV infection from their mothers each year.

There are really only two approaches to the epidemic: preventing new HIV infections and providing antiretroviral treatment to people who need it. Because there is no AIDS vaccine, prevention efforts involve education about sex, behavioral change, and reaching the groups of people, including injection-drug users and sex workers and their clients, who are at high risk for infection. Many infected people do not know that they are infected; others may not seek care, even if it is available, because of the stigma or potential repercussions.

The WHO has set a goal of providing antiretroviral treatment to 3 million people in developing countries by the end of 2005. Even if this ambitious plan succeeds, only about half the people who need treatment will be receiving it. Despite substantial progress, there remains a large gap between the number of people in developing countries who need treatment and the number being treated.

The International AIDS Conference will bring new energy, attention, and perhaps resources to the battle against the pandemic. Unfortunately, global control is not in sight.

the number of people living with the human immunodeficiency virus (HIV) infection continues to increase steadily. Two thirds of infected persons are in Africa, and one fifth are in Asia. As of the end of 2003, an estimated 34.6 million to 42.3 million people throughout the world were living with HIV infection, and more than 20 million had died of AIDS. In 2003 alone, about 4.8 million people became infected with HIV, and about 2.9 million died of AIDS. Nonetheless, the statistics are merely estimates; the situation in particular countries, such as those where accurate data are hardest to obtain, may be worse. Of all people between age 15 and 49 worldwide, 1% are now infected with HIV.

The global statistics make it clear that the burden remains greatest in Africa, although it is home to only 11 percent of the world's population.

Of the nine countries that have the most HIV-infected people, eight are in sub-Saharan Africa: South Africa, Nigeria, Zimbabwe, Tanzania, Congo, Ethiopia, Kenya, and Mozambique. Botswana, a country of less than 2 million people, has an HIV prevalence rate among adults of 37%. An estimated 950,000 people are living with HIV in the United States, 860,000 in the Russian Federation, 840,000 in China, 680,000 in Brazil, 570,000 in Thailand.

The primary modes of transmission of HIV have changed little over the years: unprotected intercourse, unprotected penetrative sex between men, injection-drug use, unsafe injections and blood transfusions, and transmission from mother to child during pregnancy, labor and delivery, or breast-feeding. Direct blood contact, such as the sharing of drug-injection equipment, is a

particularly efficient means of transmitting the virus.



Page 5

September 17, 2004; Issue 14

The New Debrecen Journal of Medicine


Is Chocolate Good For You?

Is Chocolate Good For You?

Early texts suggest that cocoa merely helped bitter medicines go down. Soon, however, cocoa was regarded as an active ingredient in cures for many illnesses. Diluted into a drink, cocoa was given to people with fevers, liver disease, and kidney disorders. Doctors prescribed ground beans mixed with resin to cure dysentery. A cocoa drink was reputed to foster needed weight gain—especially if bulked out with ground maize. Hot chocolate was even prescribed as a laxative and aid to digestion. By the early 1600s, European researchers reported that chocolate may affect mood, make people friendly and "incite consumers to lovemaking." It was reported that, as a love potion, drinking chocolate helped women conceive. If hot cocoa was drunk during pregnancy it helped smooth labour and delivery. Some decades later, articles claimed that a drink made by mixing chocolate and vanilla would strengthen the brain and womb. Mixed with Jamaican pepper, chocolate was supposed to stimulate menstrual flow and boost production of breast milk.

Few conditions are not improved by chocolate.

synthesis helps to maintain cardiovascular health by reducing blood vessel vulnerability and platelet clumping.

Chocolate is rich in saturated fatty acids, cholesterol, and sugar, and, therefore, when consumed regularly in excessive quantities, may increase the risk of developing non-insulin dependent diabetes mellitus. Limited epidemiological evidence implicates a direct association between chocolate consumption

and obesity, however. Chocolate is not an important contributor to the fat or sugar content of the adult diet. Paradoxically, despite having the highest global per capita chocolate consumption (9.9 kg a year), Switzerland has one of the lowest incidences of obesity and coronary heart disease in Western Europe whereas the USA consumes only 4.6 kg/year and has the highest mean body mass index in the Western world.

Chocolate contains about 400 different compounds that can affect mood and anxiety. These molecules selectively cause the release of chemicals, such as serotonin, endorphins, and phenylethylamine.

The botanical product was used to treat tuberculosis, toothaches, and ulcers. It was alleged to cure itches, repel tumours, and foster sleep. By the 1800s, reports emerged that chocolate could restore energy after a day of hard labour, reduce lung inflammation, or strengthen the heart. Combined with other ingredients, it became the basis of treatments for syphilis, hemorrhoids, and intestinal parasites.

Chocoholics who have given up their favorite food thinking it is bad for their health can take heart some chocolate may actually be good for

Chocolate is often said to be the most commonly craved food in the world. Several bioactive compounds in chocolate can theoretically contribute to feelings of well-being. These include the stimulants theobromine and caffeine; tyramine and phenyletylamine, which are similar to amphetamine; and anamdamide, which mimics a cannabinoid. All these compounds are present in trace amounts in chocolate and are found in many other foods. Researchers have found that cocoa filled capsules, which contain the same compounds as chocolate, did not satisfy cravings

them. Or at least for their cardiovascular system.

Chocolate and cocoa are high in flavonoids compounds found in plants that promote healthy cellular tissue throughout the body which may act as antioxidants in humans. Antioxidants help body cells resist damage by free radicals. Flavonoids also positively affect mechanisms involved in maintenance of the cardiovascular system, such as inhibition of platelet aggregation, endothelial function, and eicosanoid balance. Consumption of chocolate in cocoa beverage modifies platelet function in humans:

1. Platelet activation, as measured by platelet activation marker expression in response to weak agonists, was lower after cocoa consumption.

2. Platelet microparticle formation was reduced after cocoa consumption.

3. Consumption of cocoa caused an aspirin-like effect on platelet function.

Chocolate, especially dark chocolate and cocoa, contains a high amount of procyanidins, which help relax the wall of the aorta. This relaxation is controlled by the production of nitric oxide. Research indicates that compounds in chocolate increase nitric oxide concentrations. By activating the nitric oxide synthesis, platelet aggregation is

less likely to happen. Modulation of eicosanoid

the way chocolate did. This confirms another theory which suggests that the pleasant sensory experience of eating chocolate is necessary to satisfy the desire.

Only 15% of men crave chocolate; as many as 40% of women do, and 75% of these claim that absolutely nothing other than chocolate can satisfy their appetite. Chocolate cravings may be influenced by a deficiency in magnesium, which is prominent during premenstrual stress.

Cocoa polyphenols increase cellular antioxidant enzyme activity or antioxidant defence. Also, polyphenolic compounds of dark chocolate may prevent endothelial cell mediated LDL lipid peroxidation and thereby inhibit expression of the haemoxygenase gene. This could be important, since haemoxygenase has been linked with the transformation of monocytes to resident macrophages. Some of these effects may be relevant in preventing endothelial dysfunction and atherosclerosis development.

Not all chocolates are created equal. Nutritional values are changed by additional ingredients. Chocolate with the highest proportion of cocoa solid has the most nutritional benefit. Next time you have a chocolate craving, do not feel guilty you are doing yourself a favor.



Page 6

September 17, 2004; Issue 14

The New Debrecen Journal of Medicine


The Norwegian Baptism

(Sept 19, 2003)


Halloween

(Oct 31, 2003)



Page 7

September 17, 2004; Issue 14

The New Debrecen Journal of Medicine


GolyaBal

(Oct 18, 2003)


Soccer

(Sept 27, 2003)


Valentine's (Feb 14, 2004)



Page 8

September 17, 2004; Issue 14

The New Debrecen Journal of Medicine


Medical students today use the net a lot. That's not new. The fact that the internet is a huge labyrinth of information and that every second 20 new websites pop-up, is not new either. That is why whenever we bump into something interesting we are going according to our habit to present it to you. Don't forget, if you see something that could be interesting or helpful for others,

school/Dentistry School Reviews, Chat rooms and extensive linking.

http://www.hippocritis.com

Hmm… how can you introduce this one? Medically oriented humor by two brothers… Not everything in health is serious, and God forbid if you take diarrheas (like they say) seriously… at least in your spare time. Anyway, self-sarcasm is a good quality and the first step to a good sense of humor and knowledge of ones' self. Hippocritis, is a paraphrase of the words Hippocrates and Hypocrisy and I think it does a great job in pointing out some of the hypocrisy in medicine.

"…Consider this, by the time you finish training you will have spent one third of your life contemplating things like diarrhea. When you need to take your mind off poo, this is where to do it…".

http://groups.yahoo.com/group/esn_debrecen

The "Erasmus Student Network" of Debrecen, a Yahoo! Group of hundreds of people and lot of activity. Maybe there is a lot to learn from these people. They make their lives easier by actually communicating with each other. Erasmus students have similar problems as we do and I think an intercommunication with these guys (and girls) would be a smart thing to do.

Send us your recommended websites to our E-mail address: tndjom@yahoo.com

please let us know...

http://www.emedicine.com

E-Medicine is an online source for general medicine. It contains a huge number of articles, reviews and pictures that students and doctors might need. There is also information for lay people. Subscription is free.

http://www.gpnotebook.com

Much like E-medicine, General Physician Notebook is just more concise. It is a great site for quick reference, just like a pocket book. Check out its big brother too:

http://www.fpnotebook.com

http://www.studentdoctor.net

Student Network is a net-resource webpage for medical students. It has extensive listings of information that interest people who study, finished studying, or plan to study medicine or any other biomedical science. Stuff like forums,

med student diaries, Med-school/Pharmacy


Organ Smuggling

Greece, Albania and Italy, are three countries that until June shared something more than just their love for nice weather and trouble making! The Greek Embassy in the Albanian capital handed in an official paper to the Ministry of Health and Justice in Tirana. According to the television channel KLAN, the initial claim was, that a "doctor Mafia" exists in these three counties, whose job was to actually trade new born children.

The first complaint was made by a

transferred from country to country, to their buyers.

The initial Albanian claims, that it would be unlikely for the country to be involved, since no Albanian clinic can perform transplantation, were overthrown by the liberty of movement between the three countries. Albanian nationals, ethnically Greek or Italian were the links of a network that included at least 4 Albanian Doctors, 5 Greek ones, 5 connecting people and an Italian head.

Since June, the Interpol is involved in the research, according to which some Greek terror groups like ELA, or 17N, Italian and Albanian Mafia are also linked to this. Ever since, no further comments have been made.

The high demand for organ transplants, the continuous lack of donors (both living and cadaveric), and the possibility to make money, has turned this sensitive issue into a global problem.

Hellenic newspaper, but it wouldn't be long until the Albanian started to be interested, with the Italians joining last.

The discovery was shocking. In the best case the children themselves were traded, while in the worst one, they were part of international "organ smuggling" network. Corneas, kidneys,

blast cells and several other organs were



Page 9

September 17, 2004; Issue 14

The New Debrecen Journal of Medicine


Raising HDL

Everybody heard about LDL (the "bad" cholesterol), and about HDL (the "good" cholesterol). When either one of these exceeds its normal range, there is a high risk of severe atherosclerotic disease. It is well known that elevated levels of LDL are dangerous, but that elevated levels of HDL have a protective effect. Until today, the pharmaceutical industry only developed medications to reduce the "bad" cholesterol (these are the famous `statin' pills). However, nowadays, work is in progress to create medications that will elevate HDL, the "good" cholesterol.

The new drug which achieves this goal is called torcetrapib. It works by inhibition of cholesteryl ester transfer protein (CETP), a plasma protein that aids in the transfer of cholesterol esters from HDL to other lipoproteins. If this sounds complicated to you, just open a biochemistry book and look at the pathway of LDL, VLDL and HDL. Basically, by inhibiting CETP, the degradation of HDL is blocked, and thus, HDL levels remain high.

In a preliminary study, torcetrapib increased HDL levels and concentrations of HDL particles, and it improved lipid profiles generally. The findings suggest that this drug could substantially limit cardiovascular risk. The next step is for large clinical trials to test that possibility.

Botox

The bacterium Clostridium botulinum is notorious for its ability to produce the deadly botulinum neurotoxins. But botulinum toxin A, better known as Botox, is also universally recognized by the public as a cosmetic enhancement tool. The toxin is also used for many other medical conditions in neurology,

ophthalmology and dermatology.

The versatility of these botulinum toxins has made Clostridium botulinum one of the most widely known bacterial pathogens in medical history.

Recently, Botox has been approved for excessive sweating. This is the fourth approval for this marvel known as Botox. The Food and Drug Administration (FDA) granted its latest approval of the drug to treat primary axillary hyperhidrosis, a condition characterized by severe underarm sweating. In clinical trials, 91% of users showed a 50% reduction in armpit sweating.

Botox was first approved in 1989 to treat two eye muscle disorders. The Allergan drug has since won the FDA's approval to treat a neurological disorder that causes severe neck muscle contractions, and as a cosmetic therapy to reduce frown lines between the eyebrows.

The toxin accomplishes all these effects due to its ability to cause muscle relaxation. Used in tiny concentrations, this can be useful.

Clostridium Botulinum


Schizophrenia Tied To Flu

A recent study found that children born to mothers who had the flu during the first 20 weeks of pregnancy have a three-fold greater risk of developing schizophrenia as adults.

Researchers looked for antibodies to the influenza virus in blood samples collected from pregnant women. They then determined whether the women's children had developed schizophrenia.

Previous studies identified an association between flu during pregnancy and schizophrenia in offspring. But those studies relied on mothers' recollections of whether they had the flu while they were pregnant or examined whether the mothers of schizophrenics were pregnant during influenza outbreaks. This new study provides more conclusive evidence of the link between mothers having flu during pregnancy and schizophrenia in their children.

So, call your mom and ask her to check for influenza antibodies. This might explain everything.



Page 10

September 17, 2004; Issue 14

The New Debrecen Journal of Medicine


The FMSA - Your Student Union

This first newspaper of the year is also a good opportunity to introduce the "Foreign Medical Student Association" or FMSA. The FMSA, also known as the "student union" is devoted to help all the English program students in any possible way. The FMSA serves as the tool of connection between the students and the university. The FMSA represents the English program students in the different committees of the university.

The members of this union are foreign students like you, who care and wish to contribute and make our university a better

then move on to a different department. Today the students visit a certain department for 1 or 2 hours once a week. We never see a complete sequence of patient admission, primary investigations and initial treatment. We only "jump in" for visits, which are often not well organized and certainly non-beneficial. Not to mention the confusion of jumping from topic to topic: 2 hours orthopedics, then 2 hours urology, then 2 hours gynecology and so on. The process of changing into this block system is complex and will certainly take a long time, so be patient.

The FMSA also improves our extra-curricular life by organizing extravaganza parties several times during each semester. These are great events with music, dancing, alcohol and prizes (airplane tickets, DVDs, weekends in Budapest, movie tickets, dinners and more). Make sure not to miss these happenings. Flip to the middle pages to find a collection of pictures from last years' events.

With all this said, keep it in mind that the activity of the FMSA cannot take place without the involvement of students who invest from their private time in order to make all these events happen. There is always work to be done, and helping hands are much desired. Thus, if you feel you want to be involved and you want to contribute, please contact us.

place. In the past few years, the FMSA has helped the entire foreign student body with educational problems, but also assisted individual students in troubles they encountered in various issues.

During the past year, the FMSA has increased its strength and abilities, and became a strong union with more influence. The FMSA obtains its strength from the students' assistance and cooperation. Make our voice stronger and help us to help you!

Currently the FMSA is working with the leaders of the university to try and change the entire structure of the clinical years (4th and 5th). We hope that in the future, the education in these years will be in the "block system". This means that students will spend several continuous weeks

in each department, finish that department and

FMSA Elections!

At the end of the 3rd week, we will hold elections for the next president of the FMSA. Any student from the 3rd or 4th year who wishes to run as a candidate for this post should register at the English program secretariat until Friday, September 21, 2004.

Hey students, join the club!

The FMSA has set up a web-group for all the

students. A web-group is like a community

through which we can interact with each other. Let's say you're looking for some info about a course, or you need a book, a program, good notes, a girlfriend… you can use this internet based community to contact your classmates directly. The whole idea is about communication between students. The web-group also functions as a newsletter via which the university or the president of the FMSA can send messages. You'll get announcements, news and updates directly to your E-mail. And don't worry about spam. Everything is supervised.

How do you join? If you are a Yahoo Member then you can join through this web-address: http://groups.yahoo.com/group/debschool but if not, you

should send an empty E-mail to: debschool-subscribe@yahoogroups.com.

Good luck. See you in the group!



Page 11

September 17, 2004; Issue 14

The New Debrecen Journal of Medicine


Recommended Books

Dancing Contest!

The Washington Manual

Acclaimed as the "bible of the medical ward", the Washington Manual of Medical Therapeutics is the best-selling medical text in the world. The new 31st edition is an excellent patient management guide covering almost all medical fields. The books' pocket size, easy to use outline format, bold headings, plentiful charts and tables, and extensive index, make it a must-have

for students and young doctors.

Recommended for students from the 4th year on.

Oxford Handbook of Clinical Medicine

The Oxford Handbook of Clinical Medicine covers all areas of internal medicine and provides rapid, organized evidence based clinical management. The book was written mostly for medical students, and is meant for use on the ward, in the lecture hall, library or at home. It is concise (each topic occupies only one page!) and highly organized. The new 6th edition is a reliable `friend in the pocket' for use any time of the day or night!

Recommended for students from the 3rd year on.

Word of the FMSA President

Dear Students,

First of all, I wish to welcome all the new students and all the senior students to the new academic year 2004/2005. This new academic year is a new beginning for each one of us. A beginning of a journey which started the day we took the oath of entering the medical university of Debrecen. Only through diligence and hard work will each one of us become a proud member of the family that cherishes life - the medical doctor family.

The FMSA will try to provide you the best ground for succeeding in joining the medical doctor family. Remember, the success and strength of the FMSA depends on student cooperation and

assistance! Make our voice stronger and help us to help you!

Recently we witnessed misconduct behavior toward English Program students. Those events, as well as others in the past, were reported to the leaders of the university who contacted the police. We, as foreign students, should be more careful and aware to the people around us wherever we are. Our behavior on the university grounds and in the city should be according to our status as medical students, and so there will be no excuse for violence against us, the foreign/English program students!

Last but not least: many of the students know Professor Peter Molnar (M.D., Ph.D, C.Sc) who is the Head of the Behavioral Sciences Department. In addition Prof. Molnar was acting as the Vice Dean for Internal Affairs until recent weeks. At his position, Prof. Molnar helped every English program student, not because of his roll, but rather due to his personality and heart. Regardless of official hours, Prof. Molnars' door was always open.

The English program students and the FMSA cherish Prof. Molnar's help. We would like to thank him for all that he has done, and wish him all the best. We hope that he will continue his excellent work and remain one of the strongest allies of the foreign student community. We thank him sincerely!

Yaron Raiter

FMSA President



Page 12

September 17, 2004; Issue 14

The New Debrecen Journal of Medicine


What Is This?

Many Arab women wear a head scarf, termed a lahaaf or hejaab. It is usually secured around the head with one or two pins. This 20-year-old Arab woman presented to the emergency room after having accidentally inhaled a pin as she adjusted her scarf while holding the pin in her mouth. Postero-anterior and lateral chest radiographs showed the pin in a bronchus of the left lower lobe (arrows). The pin was removed endoscopically, without adverse consequences.

This ECG was recorded from an elderly woman who complained of dizziness.

What is your diagnosis?

This is a ventricular tachycardia with a right bundle branch block.


Where is this?

Where is this?

You walk under this lamp and pass next to this door almost every day; but... do you see them? Do you notice them?
Do you know where they are? Send your answers to: tndjom@yahoo.com. The first 3 students to send answers will win free double tickets for movies in plaza Cinema City.

This journal is made by: Ophir Bar-On (6th year) Kleonikos Tsakiris (5th year)

Orjan Waldenstrom (4th year)

Send articles and feedback to: tndjom@yahoo.com